Horizon Pharmaceuticals

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Gonadorelin

2 MG -VIALS FOR INJECTION

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Improve libido:
improve-libido

Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and luteinizing hormone from the anterior pituitary. GnRH is available as gonadorelin hydrochloride (Factrel) and gonadorelin diacetate tetrahydrate (Cystorelin) for injectable use. Studies have described it being used via an infusion pump system to induce ovulation in patients with hypothalamic hypogonadism. It is also used in veterinary medicine as a treatment for cattle with cystic ovarian disease.

Gonadorelin is responsible for the release of follicle stimulating hormone and luteinizing hormone from the anterior pituitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use.

Gonadorelin is used by women who are missing menstrual periods due to low levels of gonadotropin-releasing hormone (GnRH). It may be used as part of female infertility treatment. This medication provides GnRH that the body needs for the growth and release of mature eggs from the ovaries (ovulation).

Gonadorelin is a hormone that is produced naturally by the hypothalamus in the brain. It is also known as gonadotrophin-releasing hormone or GnRH.

Gonadorelin stimulates the pituitary gland in the brain to release the sex hormones luteinizing hormone (LH) and follicle stimulating hormone (FSH). In women, FSH stimulates the production of estrogen and the development of eggs in the ovaries. LH stimulates the ovaries to release an egg (ovulation). In men, LH stimulates the testicles to produce the hormone testosterone and FSH stimulates the testicles to produce sperm.

Reconstitution generally involves little calculation, but it is not rocket science. Let us make these calculations a little easy for you. The calculations though vary from individual to individual depending upon their goals and experiences.

The preferred method of calculation is reconstituting the 2 mg gonadorelin vial with 2 ml sterile water or bacteriostatic water. A little tip here is to clean the top of the vial with an alcohol swab to remove any contamination from bacteria before reconstitution.

You have to inject the 2 ml water in the vial at a very slow pace and leaving it for the powder to absorb the water on its own. You have to be cautious and not to shake the vial for absorption and if still any powder remains unmixed, gradually turn the vial anti-clockwise, so that the remaining powder can get mixed evenly.

The reconstituted solution of gonadorelin should always be refrigerated at around 8 degrees Celsius before and after its use. The solution should not be exposed to direct sunlight or heat as it can change the properties of the solution.

 

Biotechnological company Horizon-science is an international innovative company that unites a world-class research and development center, modern pharmaceutical and biotechnological production, preclinical and international clinical studies in compliance with contemporary standards. Horizon-science is one of the few companies in the world of a complete cycle of drugs production: from detecting molecules to mass production and marketing support. The drugs are designed to treat the most complex diseases, such as cancer, HIV, hepatitis, multiple sclerosis, etc.

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